The Tulane DECIPHeR Alliance is creating The Church-based Health Intervention to Eliminate Racial Inequalities in Cardiovascular Health (CHERISH). CHERISH is testing whether a community health worker-led church-based multifaceted implementation strategy for applying the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease will reduce cardiovascular health disparities in African Americans in New Orleans, Louisiana. The study will generate evidence on effectiveness, implementation, and sustainability of multifaceted interventions aimed at eliminating cardiovascular health disparities in African American populations in the US.